Self-assembling peptides for regeneration of the periodontal ligament: MIP: Credentis

• Research unit: INNOSUISSE
• Project number: 17310.1 PFLS-LS

Short description (German)

Self-assembling peptides for regeneration of the periodontal ligament

Short description (English)

Self-assembling peptides for regeneration of the periodontal ligament: MIP: Credentis

Abstract (German)

Periodontitis, #6 disease worldwide is an inflammatory& progressive disease of the complex tissues of the periodontal ligament potentially leading to tooth loss. An effective regenerative treatment is still rare. Self-assembling peptides have shown their potential to act as regeneration promoting matrixes. To evaluate the best suited peptide library candidate, a 3D in vitro test system will be established. Optimizations, e.g drug release of the basic peptide, will result in an optimal peptide-based product for the regeneration of periodontal tissue.

Abstract (English)

Periodontitis, #6 disease worldwide is an inflammatory& progressive disease of the complex tissues of the periodontal ligament potentially leading to tooth loss. An effective regenerative treatment is still rare. Self-assembling peptides have shown their potential to act as regeneration promoting matrixes. To evaluate the best suited peptide library candidate, a 3D in vitro test system will be established. Optimizations, e.g drug release of the basic peptide, will result in an optimal peptide-based product for the regeneration of periodontal tissue.