Self-assembling peptides for regeneration of the periodontal ligament

• Forschungsstelle: INNOSUISSE
• Projektnummer: 17310.1 PFLS-LS
• Projekttitel Englisch: Self-assembling peptides for regeneration of the periodontal ligament: MIP: Credentis

Kurzbeschreibung (Deutsch)

Self-assembling peptides for regeneration of the periodontal ligament

Kurzbeschreibung (Englisch)

Self-assembling peptides for regeneration of the periodontal ligament: MIP: Credentis

Abstract (Deutsch)

Periodontitis, #6 disease worldwide is an inflammatory& progressive disease of the complex tissues of the periodontal ligament potentially leading to tooth loss. An effective regenerative treatment is still rare. Self-assembling peptides have shown their potential to act as regeneration promoting matrixes. To evaluate the best suited peptide library candidate, a 3D in vitro test system will be established. Optimizations, e.g drug release of the basic peptide, will result in an optimal peptide-based product for the regeneration of periodontal tissue.

Abstract (Englisch)

Periodontitis, #6 disease worldwide is an inflammatory& progressive disease of the complex tissues of the periodontal ligament potentially leading to tooth loss. An effective regenerative treatment is still rare. Self-assembling peptides have shown their potential to act as regeneration promoting matrixes. To evaluate the best suited peptide library candidate, a 3D in vitro test system will be established. Optimizations, e.g drug release of the basic peptide, will result in an optimal peptide-based product for the regeneration of periodontal tissue.