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Forschungsstelle
INNOSUISSE
Projektnummer
17485.1 PFLS-LS
Projekttitel
Anti-MAG Neuropathy: Development of a Therapeutic Glycopolymer
Projekttitel Englisch
Anti-MAG Neuropathy: Development of a Therapeutic Glycopolymer: MIP: Polyneuron Pharmaceuticals AG

Texte zu diesem Projekt

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Kurzbeschreibung
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Abstract
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Erfasste Texte


KategorieText
Kurzbeschreibung
(Deutsch)
Anti-MAG Neuropathy: Development of a Therapeutic Glycopolymer
Kurzbeschreibung
(Englisch)
Anti-MAG Neuropathy: Development of a Therapeutic Glycopolymer: MIP: Polyneuron Pharmaceuticals AG
Abstract
(Deutsch)
The aim of this project is to define preclinical lead candidates for the treatment of anti-myelin-associated|glycoprotein (MAG) neuropathy, a disabling IgM autoantibody-mediated autoimmune disorder of the|peripheral nervous system. Currently, there is no effective treatment and agents to block/deplete the|pathogenic autoantibodies are of substancial clinical interest. Several lead candidates (glycopolymers) will|be synthesized and evaluated in an animal model of the disease.
Abstract
(Englisch)
The aim of this project is to define preclinical lead candidates for the treatment of anti-myelin-associated|glycoprotein (MAG) neuropathy, a disabling IgM autoantibody-mediated autoimmune disorder of the|peripheral nervous system. Currently, there is no effective treatment and agents to block/deplete the|pathogenic autoantibodies are of substancial clinical interest. Several lead candidates (glycopolymers) will|be synthesized and evaluated in an animal model of the disease.