Development of stable affinity columns for antibody purification

• Research unit: INNOSUISSE
• Project number: 17003.1 PFLS-LS

Short description (German)

Development of stable affinity columns for antibody purification

Short description (English)

Development of stable affinity columns for antibody purification

Abstract (German)

Monoclonal antibodies (MAbs) account for a large share of the rapidly growing biological drugs|market. Whilst the market for such drugs is expected to reach $62.3 billion in 2015, the biggest|obstacle in MAb production ¿ purification, is still suboptimal. Expensive Protein A resins are|used but they can be sensitive to elution and sterilization conditions. In combination with|ChromaCon¿s proprietary technology, this project aims to develop and commercialize a novel,|efficient and cost effective antibody purification process using a novel affinity reagent for|humanized antibodies.

Abstract (English)

Monoclonal antibodies (MAbs) account for a large share of the rapidly growing biological drugs|market. Whilst the market for such drugs is expected to reach $62.3 billion in 2015, the biggest|obstacle in MAb production ¿ purification, is still suboptimal. Expensive Protein A resins are|used but they can be sensitive to elution and sterilization conditions. In combination with|ChromaCon¿s proprietary technology, this project aims to develop and commercialize a novel,|efficient and cost effective antibody purification process using a novel affinity reagent for|humanized antibodies.