Development of stable affinity columns for antibody purification

• Forschungsstelle: INNOSUISSE
• Projektnummer: 17003.1 PFLS-LS
• Projekttitel Englisch: Development of stable affinity columns for antibody purification

Kurzbeschreibung (Deutsch)

Development of stable affinity columns for antibody purification

Kurzbeschreibung (Englisch)

Development of stable affinity columns for antibody purification

Abstract (Deutsch)

Monoclonal antibodies (MAbs) account for a large share of the rapidly growing biological drugs|market. Whilst the market for such drugs is expected to reach $62.3 billion in 2015, the biggest|obstacle in MAb production ¿ purification, is still suboptimal. Expensive Protein A resins are|used but they can be sensitive to elution and sterilization conditions. In combination with|ChromaCon¿s proprietary technology, this project aims to develop and commercialize a novel,|efficient and cost effective antibody purification process using a novel affinity reagent for|humanized antibodies.

Abstract (Englisch)

Monoclonal antibodies (MAbs) account for a large share of the rapidly growing biological drugs|market. Whilst the market for such drugs is expected to reach $62.3 billion in 2015, the biggest|obstacle in MAb production ¿ purification, is still suboptimal. Expensive Protein A resins are|used but they can be sensitive to elution and sterilization conditions. In combination with|ChromaCon¿s proprietary technology, this project aims to develop and commercialize a novel,|efficient and cost effective antibody purification process using a novel affinity reagent for|humanized antibodies.