Microencapsulated porcine hepatocytes for acute liver disease: development of the cell therapy product: MIP: none

• Unité de recherche: INNOSUISSE
• Numéro de projet: 17309.2 PFLS-LS
• Titre du projet anglais: Microencapsulated porcine hepatocytes for acute liver disease: development of the cell therapy product: MIP: none

Description succincte (Allemand)

Microencapsulated porcine hepatocytes for acute liver disease: development of the cell therapy product

Description succincte (Anglais)

Microencapsulated porcine hepatocytes for acute liver disease: development of the cell therapy product: MIP: none

Résumé des résultats (Abstract) (Allemand)

This project addresses the development of a microencapsulated porcine hepatocyte product for treatment of liver failure. Out of four hydrogels developed for encapsulation the best one is selected for upscale of the synthesis procedure. The product characterization aims to establish release assays in clinical application for viability, composition, and function. A flow chart will be established for the supply of donor animals that meets the microbial safety requirements.

Résumé des résultats (Abstract) (Anglais)

This project addresses the development of a microencapsulated porcine hepatocyte product for treatment of liver failure. Out of four hydrogels developed for encapsulation the best one is selected for upscale of the synthesis procedure. The product characterization aims to establish release assays in clinical application for viability, composition, and function. A flow chart will be established for the supply of donor animals that meets the microbial safety requirements.