Computerized and experimental genomic documentation package for pharmaceutical-producing cells

• Unité de recherche: INNOSUISSE
• Numéro de projet: 17196.1 PFLS-LS
• Titre du projet anglais: Computerized and experimental genomic documentation package for pharmaceutical-producing cells: MIP: Selexis AG

Description succincte (Allemand)

Computerized and experimental genomic documentation package for pharmaceutical-producing cells

Description succincte (Anglais)

Computerized and experimental genomic documentation package for pharmaceutical-producing cells: MIP: Selexis AG

Résumé des résultats (Abstract) (Allemand)

We aim to devise a computer and experimental genomic platform to characterize therapeutic-producing cells, to design improved lines for higher quality and safer therapeutic agents and to lower development costs. Our scientific aims are: i) to provide a high throughput DNA sequencing and bioinformatics platform to detect potential adventitious agents, ii) to develop more efficient genome edition procedures, so as to remove expressed viral remnants from the CHO cell genome.

Résumé des résultats (Abstract) (Anglais)

We aim to devise a computer and experimental genomic platform to characterize therapeutic-producing cells, to design improved lines for higher quality and safer therapeutic agents and to lower development costs. Our scientific aims are: i) to provide a high throughput DNA sequencing and bioinformatics platform to detect potential adventitious agents, ii) to develop more efficient genome edition procedures, so as to remove expressed viral remnants from the CHO cell genome.