QuanDecon: Quantification of isolator decontamination efficiency - Development and construction of online-sensors as well as their subsequent validation and comparison to established bio indicators

• Research unit: INNOSUISSE
• Project number: 16632.1 PFLS-LS

Short description (German)

QuanDecon: Quantification of isolator decontamination efficiency - Development and construction of online-sensors as well as their subsequent validation and comparison to established bio indicators

Short description (English)

QuanDecon: Quantification of isolator decontamination efficiency - Development and construction of online-sensors as well as their subsequent validation and comparison to established bio indicators

Abstract (German)

Decontamination with vapor phase hydrogen peroxide (VPHP) has become the first choice in a sterile pharmaceutical or medicinal production. However, recent decontamination procedures are still time-consuming as their qualification depends on bio indicators which are currently state of the art. Therefore, project goal is the development of a quantitative online sensor. The novel sensor will be compared to bio indicators and finally validated for use in an industrial production.

Abstract (English)

Decontamination with vapor phase hydrogen peroxide (VPHP) has become the first choice in a sterile pharmaceutical or medicinal production. However, recent decontamination procedures are still time-consuming as their qualification depends on bio indicators which are currently state of the art. Therefore, project goal is the development of a quantitative online sensor. The novel sensor will be compared to bio indicators and finally validated for use in an industrial production.