Establishment of a fully synthetic, mirror-image biological system - Textes

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INNOSUISSE

Numéro de projet

16101.1 PFLS-LS

Titre du projet

Establishment of a fully synthetic, mirror-image biological system

Titre du projet anglais

Establishment of a fully synthetic, mirror-image biological system

Textes relatifs à ce projet

	Allemand	Français	Italien	Anglais
Description succincte		-	-
Résumé des résultats (Abstract)		-	-

Textes saisis

Catégorie	Texte
Description succincte (Allemand)	Establishment of a fully synthetic, mirror-image biological system
Description succincte (Anglais)	Establishment of a fully synthetic, mirror-image biological system
Résumé des résultats (Abstract) (Allemand)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and\|D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from\|artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity, the most\|principal limitation of therapeutic proteins.
Résumé des résultats (Abstract) (Anglais)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and\|D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from\|artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity, the most\|principal limitation of therapeutic proteins.