Establishment of a fully synthetic, mirror-image biological system - Texte

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Forschungsstelle

INNOSUISSE

Projektnummer

16101.1 PFLS-LS

Projekttitel

Establishment of a fully synthetic, mirror-image biological system

Projekttitel Englisch

Establishment of a fully synthetic, mirror-image biological system

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-

Erfasste Texte

Kategorie	Text
Kurzbeschreibung (Deutsch)	Establishment of a fully synthetic, mirror-image biological system
Kurzbeschreibung (Englisch)	Establishment of a fully synthetic, mirror-image biological system
Abstract (Deutsch)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and\|D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from\|artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity, the most\|principal limitation of therapeutic proteins.
Abstract (Englisch)	Our goal is to create a mirror-image synthetic biology, independent of nature. Starting from L-nucleotides and\|D-amino acids, we will use chemical synthesis to establish a functioning mirror-image biological system from\|artificial components. There are immediate practical outcomes: D-DARPins will not be substrates of natural proteases, permitting oral application, and they may fundamentally overcome immunogenicity, the most\|principal limitation of therapeutic proteins.