Profiling of Synthetic Virus-like Nanoparticle Pneumococcal Vaccine Candidates

• Unité de recherche: INNOSUISSE
• Numéro de projet: 14438.1;7 PFLS-LS
• Titre du projet anglais: Profiling of Synthetic Virus-like Nanoparticle Pneumococcal Vaccine Candidates

Description succincte (Allemand)

Profiling of Synthetic Virus-like Nanoparticle Pneumococcal Vaccine Candidates

Description succincte (Anglais)

Profiling of Synthetic Virus-like Nanoparticle Pneumococcal Vaccine Candidates

Résumé des résultats (Abstract) (Allemand)

Virometix AG is developing a broad-spectrum pneumococcal vaccine based on its synthetic virus-like particle (SVLP) technology, comprising surface proteins (virulence factors) that are commonly expressed by all pneumococcal serotypes. The vaccine should overcome major shortcomings of the current capsular polysaccharide-based vaccines including limited serotype coverage and high manufacturing complexity. This KTI project should support preclinical profiling of Virometix vaccine candidates in animal models of pneumococcal diseases.

Résumé des résultats (Abstract) (Anglais)

Virometix AG is developing a broad-spectrum pneumococcal vaccine based on its synthetic virus-like particle (SVLP) technology, comprising surface proteins (virulence factors) that are commonly expressed by all pneumococcal serotypes. The vaccine should overcome major shortcomings of the current capsular polysaccharide-based vaccines including limited serotype coverage and high manufacturing complexity. This KTI project should support preclinical profiling of Virometix vaccine candidates in animal models of pneumococcal diseases.