A novel cell penetrating peptide as vector for therapeutic cancer vaccine: a proof-of-concept

• Unité de recherche: INNOSUISSE
• Numéro de projet: 13070.1;6 PFLS-LS
• Titre du projet anglais: A novel cell penetrating peptide as vector for therapeutic cancer vaccine: a proof-of-concept

Description succincte (Anglais)

A novel cell penetrating peptide as vector for therapeutic cancer vaccine: a proof-of-concept

Description succincte (Français)

A novel cell penetrating peptide as vector for therapeutic cancer vaccine: a proof-of-concept

Résumé des résultats (Abstract) (Anglais)

Seen as promising therapy, different therapeutic cancer vaccine approaches have been developed and evaluated to teach the killer cells of the immune system to specifically recognize and attack the tumor cells. Tumor specific killer cells were often described however, only occasionally correlating with tumor regression.It is in this context that we aim to develop an innovative proprietary 2nd generation cancer-vaccine platform, based on a new cell penetrating peptide fused to a protein to achieve multi-epitopic, multi-allelic and polyfunctional antitumor immunity.

Résumé des résultats (Abstract) (Français)

Seen as promising therapy, different therapeutic cancer vaccine approaches have been developed and evaluated to teach the killer cells of the immune system to specifically recognize and attack the tumor cells. Tumor specific killer cells were often described however, only occasionally correlating with tumor regression.It is in this context that we aim to develop an innovative proprietary 2nd generation cancer-vaccine platform, based on a new cell penetrating peptide fused to a protein to achieve multi-epitopic, multi-allelic and polyfunctional antitumor immunity.