CAMEO- ChAracterization and optimization of selective and safe Modulators of the innate immune system for treatment of cancer and other disEases: a combined mOdelling/experimental study

• Research unit: INNOSUISSE
• Project number: 13240.1;10 PFLS-LS

Short description (English)

CAMEO- ChAracterization and optimization of selective and safe Modulators of the innate immune system for treatment of cancer and other disEases: a combined mOdelling/experimental study

Short description (French)

CAMEO- Characterization and optimization of selective and safe Modulators of the innate immune system for treatment of cancer and other diseases: a combined modelling/experimental study

Abstract (English)

The aim of this project is the characterization and optimization of Toll-like receptor 7 modulators¿ structure. Computational modeling, in synergy with cellular and molecular biology will provide detailed molecular information about their self-assembly properties, their interaction with the receptors and off-target problems. This knowledge will accelerate and focus the drugs optimization process leading to the GLP IND -enabling studies for entering subsequent clinical phases

Abstract (French)

The aim of this project is the characterization and optimization of Toll-like receptor 7 modulators¿ structure. Computational modeling, in synergy with cellular and molecular biology will provide detailed molecular information about their self-assembly properties, their interaction with the receptors and off-target problems. This knowledge will accelerate and focus the drugs optimization process leading to the GLP IND -enabling studies for entering subsequent clinical phases