Quantitative stool extraction Device (SED)

• Forschungsstelle: INNOSUISSE
• Projektnummer: 13504.1;15 PFFLE-LS
• Projekttitel Englisch: Quantitative stool extraction Device (SED)

Kurzbeschreibung (Deutsch)

Quantitative stool extraction Device (SED)

Kurzbeschreibung (Englisch)

Quantitative stool extraction Device (SED)

Abstract (Deutsch)

(Feasibility to Prototype Study, 12 months). This project pursues the development of a POC (point of care) capable, quantitative, inexpensive Stool Extraction Device (SED), particularly to extract Calprotectin (MRP8/14; S100A8/A9) from pathological stool samples of IBD patients. Such stool samples are not homogenous, can be fluid, chewy or solid and may contain fibers or grains reducing the net volume of stool. As a first step, we will develop in silico feasibility of POC capable SED (3 months). As a second step, a breadboard prototype is manufactured to technically validate all process steps including its functionality on pipetting robots (3-6 months). As a third step, a rapid prototype is manufactured to clinically validate the SED (3-6 months). (Implementation of a Production Line, 6 months). As the last step, all parts of the SED will be manufactured, filled and assembled on a production line to be built by a specialized company (forteq AG, CH-Nidau).

Abstract (Englisch)

(Feasibility to Prototype Study, 12 months). This project pursues the development of a POC (point of care) capable, quantitative, inexpensive Stool Extraction Device (SED), particularly to extract Calprotectin (MRP8/14; S100A8/A9) from pathological stool samples of IBD patients. Such stool samples are not homogenous, can be fluid, chewy or solid and may contain fibers or grains reducing the net volume of stool. As a first step, we will develop in silico feasibility of POC capable SED (3 months). As a second step, a breadboard prototype is manufactured to technically validate all process steps including its functionality on pipetting robots (3-6 months). As a third step, a rapid prototype is manufactured to clinically validate the SED (3-6 months). (Implementation of a Production Line, 6 months). As the last step, all parts of the SED will be manufactured, filled and assembled on a production line to be built by a specialized company (forteq AG, CH-Nidau).