A new manufacturing equipment for liquid and semi-solid pharmaceutical products: process analytical combination of on-line Resonator Technology with real shear and Coriolis force measurement

• Research unit: INNOSUISSE
• Project number: 13154.1;5 PFFLE-IW

Short description (German)

A new manufacturing equipment for liquid and semi-solid pharmaceutical products: process analytical combination of on-line Resonator Technology with real shear and Coriolis force measurement

Short description (English)

A new manufacturing equipment for liquid and semi-solid pharmaceutical products: process analytical combination of on-line Resonator Technology with real shear and Coriolis force measurement

Abstract (German)

The currenz project develops an on-line version of Ultrasonic Resonator Technology using a pilot-scale manufacturing vessel for liquid and semi-solid products. Moreover, on-line real shear and Coriolis force sensors are evaluated with respect to providing complementary information to the ultrasound analysis. This fully instrumented mixing and homogenization vessel provides unique manufacturing equipment to the pharmaceutical industry. A high impact us expected on pharmaceutical process development as well as on commercial manufacturing.

Abstract (English)

The currenz project develops an on-line version of Ultrasonic Resonator Technology using a pilot-scale manufacturing vessel for liquid and semi-solid products. Moreover, on-line real shear and Coriolis force sensors are evaluated with respect to providing complementary information to the ultrasound analysis. This fully instrumented mixing and homogenization vessel provides unique manufacturing equipment to the pharmaceutical industry. A high impact us expected on pharmaceutical process development as well as on commercial manufacturing.