Multimodal catheter for cardiovascular diagnosis

• Forschungsstelle: INNOSUISSE
• Projektnummer: 13757.1;5 PFFLE-LS
• Projekttitel Englisch: Multimodal catheter for cardiovascular diagnosis

Kurzbeschreibung (Deutsch)

Multimodal catheter for cardiovascular diagnosis

Kurzbeschreibung (Englisch)

Multimodal catheter for cardiovascular diagnosis

Abstract (Deutsch)

Vulnerable plaque and stenosis reduce the cross-section of blood vessels and is one of the main origins of cardio-vascular diseases such as myocardial infarction, stroke and cardiac death. Diagnosis using stress tests or coronary angiography allow large-scale screening and identify patients at risk. However, direct and fast characterization of the clinical relevance of the coronary lesion is still an unsolved issue in many patients. This project aims mounting hot filament anemometry devices onto an existing commercial guide wire allowing real-time monitoring of the local speed of the flowing blood in the vessel. According to Bernoulli the local speed of a liquid is directly linked to cross-section reduction of a vessel. Marking the position of this throat allows subsequent clinical decision making for treatment. In a second step, the deposition of thin-film ultrasound pulse-echo devices onto the guide wire is projected to complete global clinical diagnosis.

Abstract (Englisch)

Vulnerable plaque and stenosis reduce the cross-section of blood vessels and is one of the main origins of cardio-vascular diseases such as myocardial infarction, stroke and cardiac death. Diagnosis using stress tests or coronary angiography allow large-scale screening and identify patients at risk. However, direct and fast characterization of the clinical relevance of the coronary lesion is still an unsolved issue in many patients. This project aims mounting hot filament anemometry devices onto an existing commercial guide wire allowing real-time monitoring of the local speed of the flowing blood in the vessel. According to Bernoulli the local speed of a liquid is directly linked to cross-section reduction of a vessel. Marking the position of this throat allows subsequent clinical decision making for treatment. In a second step, the deposition of thin-film ultrasound pulse-echo devices onto the guide wire is projected to complete global clinical diagnosis.