Antimicrobial silver surface treatment of orthopaedic implants (PROSILVER)

• Research unit: INNOSUISSE
• Project number: 13374.1 PFNM-NM

Short description (German)

Antimicrobial silver surface treatment of orthopaedic implants (PROSILVER)

Short description (English)

Antimicrobial silver surface treatment of orthopaedic implants (PROSILVER)

Abstract (German)

An antibacterial surface treatment consisting of silver immobilized in an organic linker (INA)* and ligand (L1)*|is applied on TiAlNb and CoCrMo orthopaedic alloys via a solution process designed to combat|periprosthetic infection which is the main cause of revision in total hip and knee arthroplasty.|While the concept has demonstrated to be feasible in vitro on lab scale, the project will determine safety and|efficacy through biocompatibility and animal studies of the industrial scale by integrating the process on an|existing orthopaedic production line.|*see Background IP in exhibit 3

Abstract (English)

An antibacterial surface treatment consisting of silver immobilized in an organic linker (INA)* and ligand (L1)*|is applied on TiAlNb and CoCrMo orthopaedic alloys via a solution process designed to combat|periprosthetic infection which is the main cause of revision in total hip and knee arthroplasty.|While the concept has demonstrated to be feasible in vitro on lab scale, the project will determine safety and|efficacy through biocompatibility and animal studies of the industrial scale by integrating the process on an|existing orthopaedic production line.|*see Background IP in exhibit 3