Development of a medical grade autoclave to produce and validate cellular biocomposites for human bone replacement. (Medautoclave biocomposites)

• Research unit: INNOSUISSE
• Project number: 13556.1;5 PFFLI-LS

Short description (English)

Development of a medical grade autoclave to produce and validate cellular biocomposites for human bone replacement. (Medautoclave biocomposites)

Short description (French)

Development of a medical grade autoclave to produce and validate cellular biocomposites for human bone replacement. (Medautoclave biocomposites)

Abstract (English)

A novel biocomposite material has been developed at EPFL for bone replacement. The bioresorbable material was validated by in vivo tests on small and large animals. This CTI project proposes to design a reliable medical grade autoclave for GMP production of the biocomposite scaffold and then to validate both during a human clinical study. The outcomes will be new components and systems for high-pressure medical equipment, reliable GMP biocomposites and technical/clinical information for the future marking and commercialisation of the biocomposite implants. SITEC-Sieber Engineering and EPFL-LTC are the main partners, EPFL-LBO, CHUV and other suppliers are involved in the project.

Abstract (French)

A novel biocomposite material has been developed at EPFL for bone replacement. The bioresorbable material was validated by in vivo tests on small and large animals. This CTI project proposes to design a reliable medical grade autoclave for GMP production of the biocomposite scaffold and then to validate both during a human clinical study. The outcomes will be new components and systems for high-pressure medical equipment, reliable GMP biocomposites and technical/clinical information for the future marking and commercialisation of the biocomposite implants. SITEC-Sieber Engineering and EPFL-LTC are the main partners, EPFL-LBO, CHUV and other suppliers are involved in the project.