A Feasibility Study on Continuous Clinical Monitoring of Cerebral Compliance in Patients with Traumatic Brain Injury

• Research unit: INNOSUISSE
• Project number: 12105.1;5 PFLS-LS

Short description (German)

A Feasibility Study on Continuous Clinical Monitoring of Cerebral Compliance in Patients with Traumatic Brain Injury

Short description (English)

A Feasibility Study on Continuous Clinical Monitoring of Cerebral Compliance in Patients with Traumatic Brain Injury

Abstract (German)

Traumatic brain injury (TBI) is the leading cause of death and disability among children and young adults. The principal objective in TBI treatment is the prevention of secondary insult through brain swelling and impairment of the intracranial regulatory processes, as this may lead to permanent brain damage or death. While currently intracranial pressure is monitored for indication of potential brain damage, cerebral compliance has been suggested as a better, more accurate and sensitive predictor. In this study, an innovative method for measuring continuous cerebral compliance will be evaluated for its potential use in the clinical environment.

Abstract (English)

Traumatic brain injury (TBI) is the leading cause of death and disability among children and young adults. The principal objective in TBI treatment is the prevention of secondary insult through brain swelling and impairment of the intracranial regulatory processes, as this may lead to permanent brain damage or death. While currently intracranial pressure is monitored for indication of potential brain damage, cerebral compliance has been suggested as a better, more accurate and sensitive predictor. In this study, an innovative method for measuring continuous cerebral compliance will be evaluated for its potential use in the clinical environment.