Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation. - Texts

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Research unit

INNOSUISSE

Project number

11098.1;11 PFLS-LS

Project title

Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.

Texts for this project

	German	French	Italian	English
Short description		-	-
Abstract		-	-	-

Inserted texts

Category	Text
Short description (German)	Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.
Short description (English)	Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.
Abstract (German)	This project is to develop an innovative orthopaedic implant composed of a metal bone screw and a biodegradable drug delivery system to locally administer Bisphosphonates. Implant surfaces will be modified with selected poly-lactides offering a variety of degradation features, making them ideal candidates for hosting and releasing pharmaceutical agents. The bio-coating will be analyzed by means of physical, chemical and pharmaceutical means. Finally, safety and efficacy of the bioactive coating will be demonstrated in a preclinical investigation.