Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.

Forschungsstelle

INNOSUISSE

Projektnummer

11098.1;11 PFLS-LS

Projekttitel

Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.

Projekttitel Englisch

Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung		-	-
Abstract		-	-	-

Kategorie	Text
Kurzbeschreibung (Deutsch)	Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.
Kurzbeschreibung (Englisch)	Development of a biodegradable drug delivery system on metal implants supporting bone regeneration and enhancing fixation.
Abstract (Deutsch)	This project is to develop an innovative orthopaedic implant composed of a metal bone screw and a biodegradable drug delivery system to locally administer Bisphosphonates. Implant surfaces will be modified with selected poly-lactides offering a variety of degradation features, making them ideal candidates for hosting and releasing pharmaceutical agents. The bio-coating will be analyzed by means of physical, chemical and pharmaceutical means. Finally, safety and efficacy of the bioactive coating will be demonstrated in a preclinical investigation.