Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

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Unité de recherche

INNOSUISSE

Numéro de projet

10776.1;7 PFLS-LS

Titre du projet

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Titre du projet anglais

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Textes relatifs à ce projet

	Allemand	Français	Italien	Anglais
Description succincte	-	-	-
Résumé des résultats (Abstract)	-	-	-

Textes saisis

Catégorie	Texte
Description succincte (Anglais)	Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia
Résumé des résultats (Abstract) (Anglais)	This is a development project for use of MDPK67b to diminish the effects of neutropenia provoked by treatment with chemotherapeutic agents. The effects of MDPK67b on myeloid cells will be investigated in vitro, with the aim of elucidating the mechanism of action. In vivo proof of concept studies will be performed in mice and marmoset models. At the successful completion of this project, MDPK67b is expected to be able to enter into clinical trials for this indication.

Catégorie

Texte

Description succincte
(Anglais)

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Résumé des résultats (Abstract)
(Anglais)

This is a development project for use of MDPK67b to diminish the effects of neutropenia provoked by treatment with chemotherapeutic agents. The effects of MDPK67b on myeloid cells will be investigated in vitro, with the aim of elucidating the mechanism of action. In vivo proof of concept studies will be performed in mice and marmoset models. At the successful completion of this project, MDPK67b is expected to be able to enter into clinical trials for this indication.