Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

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Forschungsstelle

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Projektnummer

10776.1;7 PFLS-LS

Projekttitel

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Projekttitel Englisch

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung	-	-	-
Abstract	-	-	-

Erfasste Texte

Kategorie	Text
Kurzbeschreibung (Englisch)	Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia
Abstract (Englisch)	This is a development project for use of MDPK67b to diminish the effects of neutropenia provoked by treatment with chemotherapeutic agents. The effects of MDPK67b on myeloid cells will be investigated in vitro, with the aim of elucidating the mechanism of action. In vivo proof of concept studies will be performed in mice and marmoset models. At the successful completion of this project, MDPK67b is expected to be able to enter into clinical trials for this indication.

Kategorie

Text

Kurzbeschreibung
(Englisch)

Development of recombinant serpin MDPK67b for treatment of chemotherapy induced neutropenia

Abstract
(Englisch)

This is a development project for use of MDPK67b to diminish the effects of neutropenia provoked by treatment with chemotherapeutic agents. The effects of MDPK67b on myeloid cells will be investigated in vitro, with the aim of elucidating the mechanism of action. In vivo proof of concept studies will be performed in mice and marmoset models. At the successful completion of this project, MDPK67b is expected to be able to enter into clinical trials for this indication.