Quantitative surface functionalization of microcarriers for simultaneously detection of various specific biomarkers

• Research unit: INNOSUISSE
• Project number: 9785.1;5 PFLS-LS

Short description (English)

Quantitative surface functionalization of microcarriers for simultaneously detection of various specific biomarkers

Short description (French)

Quantitative surface functionalization of microcarriers for simultaneously detection of various specific biomarkers

Abstract (French)

Biocartis has developed a proprietary system for multiplexed analysis of blood. This system enables the determination of several biomarkers from the same sample in a fast and cheap way. The key of this invention is encoded microcarriers. Each code represents a specific adsorption of a biomarker. The system is composed of three subunits: the coded microcarriers, their functionalization and the biological readout device. The surface functionalization needs further development. The reasons are that the functionalization must lead to a quantitative and specific adsorption of antigens and the functionalization method must be independently from the original chemical surface properties of the microcarriers. This project aims to develop a cheap and robust functionalization method which allows a quantitative and specific adsorption of antigens in blood plasma.