IN3 : Intelligent INvitro INcubator

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Forschungsstelle

INNOSUISSE

Projektnummer

9707.1;8 PFLS-LS

Projekttitel

IN3 : Intelligent INvitro INcubator

Projekttitel Englisch

IN3 : Intelligent INvitro INcubator

Texte zu diesem Projekt

	Deutsch	Französisch	Italienisch	Englisch
Kurzbeschreibung	-	-	-
Abstract	-	-	-

Erfasste Texte

Kategorie	Text
Kurzbeschreibung (Englisch)	IN3 : Intelligent INvitro INcubator
Abstract (Englisch)	Infertility has dramatically increased during the last decades and currently about 20% of couples struggle with infertility at any given time, making in vitro fertilization (IVF) their only option to conceive. IVF techniques require numerous interventions by the biologist, including direct manipulation of gametes, zygotes and embryos, as well as their regular observation to monitor morphology and development throughout the culture period. During the extracorporeal phase of IVF, gametes and embryos are stored in incubators, where the optimal conditions of temperature, CO2 concentration and humidity are maintained. The stability of these conditions is crucial in determining oocyte growth and embryo viability, and repeated exposure to external environment may have severe negative effects on further development. The main goal of the IN3 project is to reengineer the IVF process in the following directions: 1) To develop an incubator equipped with an internal microscope 2) To design and organize a multimedia database to store and intelligently retrieve physiological parameters 3) To implement and validate an automatic classification systems to evaluate embryos 4) To implement a decision support system that could assist the biologist in correlating the parameters collected during the culture period with implantation 5) To develop a manipulator inside the incubator. IN3 is an innovative project aimed at minimizing gamete/zygote/embryo exposure to external conditions.

Kategorie

Text

Kurzbeschreibung
(Englisch)

IN3 : Intelligent INvitro INcubator

Abstract
(Englisch)

Infertility has dramatically increased during the last decades and currently about 20% of couples struggle with infertility at any given time, making in vitro fertilization (IVF) their only option to conceive. IVF techniques require numerous interventions by the biologist, including direct manipulation of gametes, zygotes and embryos, as well as their regular observation to monitor morphology and development throughout the culture period. During the extracorporeal phase of IVF, gametes and embryos are stored in incubators, where the optimal conditions of temperature, CO2 concentration and humidity are maintained. The stability of these conditions is crucial in determining oocyte growth and embryo viability, and repeated exposure to external environment may have severe negative effects on further development. The main goal of the IN3 project is to reengineer the IVF process in the following directions: 1) To develop an incubator equipped with an internal microscope 2) To design and organize a multimedia database to store and intelligently retrieve physiological parameters 3) To implement and validate an automatic classification systems to evaluate embryos 4) To implement a decision support system that could assist the biologist in correlating the parameters collected during the culture period with implantation 5) To develop a manipulator inside the incubator. IN3 is an innovative project aimed at minimizing gamete/zygote/embryo exposure to external conditions.