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Research unit
INNOSUISSE
Project number
9318.1;8 PFLS-LS
Project title
Photodynamic therapy based uveitis treatment

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Short description
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Abstract
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CategoryText
Short description
(English)
Photodynamic therapy based uveitis treatment
Short description
(French)
Photodynamic therapy based uveitis treatment
Abstract
(English)
Uveitis is an inflammatory eye disease leading to blindness. It has no satisfactory treatment options. OPPH proposes to adapt photodynamically active Hynospheres as a competent uveitis therapy. This project proposes to carry out a dose range-finding study in an animal model of uveitis. These results will be used to design pre-clinical IND enabling safety studies . Clinical trials will then be initiated.
Abstract
(French)
Uveitis is an inflammatory eye disease leading to blindness. It has no satisfactory treatment options. OPPH proposes to adapt photodynamically active Hynospheres as a competent uveitis therapy. This project proposes to carry out a dose range-finding study in an animal model of uveitis. These results will be used to design pre-clinical IND enabling safety studies . Clinical trials will then be initiated.