Tissue engineering of meniscus using the Chondro-Gide® membrane ¿ steps towards human clinical trials in orthopedics

Font Standard Bold
Login

Research unit

INNOSUISSE

Project number

7430.1;5 LSPP-LS

Project title

Tissue engineering of meniscus using the Chondro-Gide® membrane ¿ steps towards human clinical trials in orthopedics

Texts for this project

	German	French	Italian	English
Short description	-	-	-
Abstract	-	-	-

Inserted texts

Category	Text
Short description (English)	Tissue engineering of meniscus using the Chondro-Gide® membrane-steps towards human clinical trials in orthopedics.
Abstract (English)	The long-term repair of meniscal lesions is still unsatisfactory. Successful regeneration of hyaline cartilage employing the Chondro-Gide® and autologous chondrocyte transplantation (ACT), has precipitated the concept of an ACT-based tissue-guided reconstruction of meniscus. An in vivo safety animal study and in vitro studies to identify the best clinically relevant cell source for meniscal fibrocartilage regeneration will be performed. Results will identify future avenues towards development of the tissue engineered fibrocartilage for clinical trials.

Category

Text

Short description
(English)

Tissue engineering of meniscus using the Chondro-Gide® membrane-steps towards human clinical trials in orthopedics.

Abstract
(English)

The long-term repair of meniscal lesions is still unsatisfactory. Successful regeneration of hyaline cartilage employing the Chondro-Gide® and autologous chondrocyte transplantation (ACT), has precipitated the concept of an ACT-based tissue-guided reconstruction of meniscus. An in vivo safety animal study and in vitro studies to identify the best clinically relevant cell source for meniscal fibrocartilage regeneration will be performed. Results will identify future avenues towards development of the tissue engineered fibrocartilage for clinical trials.