Catalysis as the Key to Highly Selective and Ecologically Benign Processes

• Unité de recherche: COST
• Numéro de projet: C02.0060
• Titre du projet anglais: Catalysis as the Key to Highly Selective and Ecologically Benign Processes

Mots-clé (Anglais)

atropisomers; catalysis; chirality; ecology; economy; phosphines

Programme de recherche (Anglais)

COST-Action D24 - Sustainable Chemical Processes: Stereoselective Transition Metal-Catalysed Reactions

Description succincte (Anglais)

See abstract

Partenaires et organisations internationales (Anglais)

AT, BE, DK, FI, FR, DE, EL, HU, IE, IT, LV, MT, NL, NO, PL, PT, RO, SI, ES, SE, CH, UK

Résumé des résultats (Abstract) (Anglais)

Racemic diallyl and di(2-methylallyl) 1,1'-binaphthyl-2,2'-diyl diethers undergo a diastereoselective Wittig rearrangement. After Sharpless-Katsuki epoxydation, one enantiomer can be recovered unchanged and subsequently oxidized to afford chirally pure 1,1'-binaphthyl-2,2'-dicarboxylic acid. Hydrogenation of the intermediate and base-promoted condensation with chlorodiphenylphosphine leads into the little explored, but promising class of atropisomeric phosphinites. Due to the retirement of the subsidy recipient, no research work was carried out in the laboratory during all 2006. On the other hand, the results previously obtained were disseminated by lectures and printed publications.

Références bases de données (Anglais)

Swiss Database: COST-DB of the State Secretariat for Education and Research Hallwylstrasse 4 CH-3003 Berne, Switzerland Tel. [phone] Swiss Project-Number: C02.0060