MAAPHRI: Multidisciplinary Approach to Airborne Pollutant Health Related Issues: Modelization with Combustion Engine Exhausts

• Research unit: EU RFP
• Project number: 02.0449

Key words (English)

Environmental Protection; Life Sciences; Medicine; Health; Safety

Alternative project number (English)

EU project number: QLK4-CT-2002-02357

Research programs (English)

EU-programme: 5. Frame Research Programme - 1.1.4 Environment and health

Short description (English)

See abstract

Further information (English)

Full name of research-institution/enterprise:
Université de Lausanne
Institut de Pharmacologie et de Toxicologie

Abstract (English)

The following key questions will be addressed:
- Improvement of complex atmosphere continuous sampling for specific in vitro alternative testing developments using both animal and human material risk assessment of global engine exhaust modulation strategies (fuel composition, engine technologies, after-treatment strategies);
- Dissection of hazardous engine exhaust components and understanding of their relative contribution to toxicity (gaseous phase, PM size, PM chemical composition);
- Comparative assessment of exhaust components in animals with chronic cardiorespiratory diseases: allergy, cardiac insufficiency to modelise at risk populations;
- Elaboration of strategies based on health/toxicity indicators for developing cleaner engine-fuel-exhaust gas after treatment concepts guaranteeing that harmful components are not emitted.

References in databases (English)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 02.0449