EURO GENE DRUG: Novel gene drug strategy based on hybridisation of functional entities to plasmids

• Research unit: EU RFP
• Project number: 02.0276

Key words (English)

Biotechnology; Environmental Protection; Innovation; Technology Transfer; Life Sciences; Medicine; Health; Waste Management

Alternative project number (English)

EU project number: QLK3-CT-2002-01997

Research programs (English)

EU-programme: 5. Frame Research Programme - 1.1.3 The 'cell factory'

Short description (English)

See abstract

Abstract (English)

Gene therapy is an emerging technology with the potential of having an important impact on future treatments of human diseases. Efficient gene transfer relies on optimal receptor-binding, intracellular vesicular transport and nuclear uptake. According to these requirements, a novel GENE DRUG therapeutic strategy will be developed. This strategy is ased on a patented plasmid delivery system in which functional entities, improving delivery efficiency, are attached to the plasmid by means of hybridisation. The proposal is focused on the delivery of therapeutic genes for cardiovascular diseases and haemophilia.

References in databases (English)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 02.0276