EDEN: Endocrine disrupters: exploring novel endpoints, exposure, low-dose- and mixture-effects in humans, aquatic wildlife and laboratory animals

• Research unit: EU RFP
• Project number: 01.0376-2

Key words (English)

Environmental Protection; Life Sciences; Medicine; Health; Safety

Alternative project number (English)

EU project number: 01QLK4-CT-2002-00603

Research programs (English)

EU-programme: 5. Frame Research Programme - 1.1.4 Environment and health

Short description (English)

See abstract

Further information (English)

Full name of research-institution/enterprise:
Universität Bern
Institut fur Tierpathologie
Zentrum für Fisch und Wildtiermedizin

Abstract (English)

In the EU, there are significant human and wildlife health problems that stem from 'endocrine disruption'. What is unresolved is whether human/wildlife exposure to endocrine disrupting chemicals (EDC) from the environment plays any causal role in these developmental disorders. The motivation of EDEN is to meet this challenge by addressing common problems in wildlife and human hazard assessment in one coherent approach. It will produce data about the occurrence of mixed exposures to EDC in humans and fish and develop new experimental models that allow more meaningful extrapolations from animals to humans. It will produce data about low-dose- and mixture effects of EDC that are directly relevant to hazard and risk assessment. It will provide new insights into indicators of reproductive health of European citizens and will help to produce the scientific basis for a coherent strategy for dealing with EDC in the EU.

References in databases (English)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 01.0376-2