LIPIDIET: The role of lipids in prevention of degeneration by diet

• Research unit: EU RFP
• Project number: 00.0297

Key words (English)

Agriculture; Economic Aspects; Food; Industrial Manufacture; Life Sciences; Medicine; Health; Safety;
Agriculture; Economic Aspects; Food; Industrial Manufacture; Life Sciences; Medicine; Health; Safety

Alternative project number (English)

EU project number: QLK1-CT-2001-00172

Research programs (English)

EU-programme: 5. Frame Research Programme - 1.1.1 Food, nutrition and health

Short description (English)

See abstract

Abstract (English)

To prevent and treat age associated neurodegenerative diseases is a key challenge of this century. Based on recent findings it is promising to develop dietary lipid related disease prevention strategies. The present project will undertake this strategic approach, which will first be applied to AlzheimerÕs disease, in which brain lipids are believed to play an important role. Three converging lines of investigation will be pursued. In vitro studies of the role of lipids in neuronal degeneration and of the effects thereon of distinct lipid related treatments would be preformed first. The resulting promising treatments will than be used for the preparation of formulations whose effectiveness will be tested in vivo utilizing distinct models of neurodegeneration and dementia. The best diets will be tested in man for their ability to halt and prevent disease.

References in databases (English)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 00.0297