DEVELOPMENT OF NEW ANTI-PROTEASE MOLECULES FOR THE TREATMENT OF DISEASES INVOLVING PROTEASE ACTIVITY DYSREGULATION.

• Research unit: INNOSUISSE
• Project number: 6294.5;9 BTS-LS

Short description (English)

DEVELOPMENT OF NEW ANTI-PROTEASE MOLECULES FOR THE TREATMENT OF DISEASES INVOLVING PROTEASE ACTIVITY DYSREGULATION.

Short description (French)

Developpement de nouvelles molecules therapeutiques de type anti-proteases pour le traitement de maladies impliquant l'action de proteases

Abstract (English)

Until now, more than 25'000 pathologies have been identified but only a few thousand have an effective treatment. Of all proteins expressed by living organisms, proteases are among the most important in mediating pathways of cell life and death. Among the 400 different human proteases already identified, it is estimated that about 15% would play a major role in the pathogenicity of human diseases which makes them attractive targets for drug development.