DIADEM: Early diagnosis of Alzheimer's disease and related dementia

• Unité de recherche: PCRD EU
• Numéro de projet: 00.0525-1
• Titre du projet anglais: DIADEM: Early diagnosis of Alzheimer's disease and related dementia

Mots-clé (Anglais)

Alzheimer's; diagnostic tools; therapeutic strategies;
Biotechnology; Environmental Protection; Innovation; Technology Transfer; Life Sciences; Medicine; Health; Waste Management

Autre Numéro de projet (Anglais)

EU project number: QLK3-CT-2001-02362

Programme de recherche (Anglais)

EU-programme: 5. Frame Research Programme - 1.1.3 The 'cell factory'

Description succincte (Anglais)

See abstract

Partenaires et organisations internationales (Anglais)

Coordinator: VERUM, München (D)

Résumé des résultats (Abstract) (Anglais)

Alzheimer's disease (AD) and related dementia are irreversible, degenerative disorders of the brain characterised by progressive cognitive decline, the loss of personality and finally death. Because of the impact on individuals and due to the enormous costs for health care and thus for society, these disorders present a major health problem to the EU. Treatment that can prevent, arrest and reverse degeneration and death of neurons is therefore urgently required. Prerequisite is the development of diagnostic tools that identify patients at an early pre-symptomatic stage. A consortium of 21 of the most experienced AD laboratories from Europe and beyond will carry out a research project integrating data from studies with tissue cultures and genetically modified animals into a clinical investigation of demented patients. A broad array of bio - technological methods will be used. Results of these studies will lead to diagnostic screening strategies combining genetic, pathophysiological and biomarker information.

Références bases de données (Anglais)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 00.0525-1