MEMPROT-NET: The targeting and biosynthesis of membrane and secretory proteins

• Research unit: EU RFP
• Project number: 00.0258

Key words (English)

Protein synthesis; membrane proteins; secretory proteins; signal recognition particle;
Biotechnology; Environmental Protection; Innovation; Technology Transfer; Life Sciences; Medicine; Health; Waste Management

Alternative project number (English)

EU project number: QLK3-2000-00082

Research programs (English)

EU-programme: 5. Frame Research Programme - 1.1.3 The 'cell factory'

Short description (English)

See abstract

Further information (English)

Full name of research-institution/enterprise:
Université de Genève
Faculté des Sciences
Département de Biologie cellulaire / Sciences III

Partners and International Organizations (English)

Coordinator: Victoria University of Manchester (UK)

Abstract (English)

Our objective is to - provide a detailed understanding of the biosynthesis of membrane and secretory proteins.

The focus will be:
1) components
2) molecular mechanisms and
3) regulation.

A detailed molecular understanding of these key issues is currently lacking. Furthermore, although membrane protein biosynthesis is directly relevant to exploiting the cell factory, little effort has been made to establish whether this process can be engineered. We will achieve our objective by focusing the research efforts of individual teams into a co-ordinated research programme.

The teams provide several different biological systems, enabling information and technology transfer, and represent all of the disciplines crucial to the project:
biochemistry;
cell biology;
microbiology;
structural biology;
bio-computing and commercial exploitation.

References in databases (English)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 00.0258