MEMPROT-NET: The targeting and biosynthesis of membrane and secretory proteins

• Forschungsstelle: EU FRP
• Projektnummer: 00.0258
• Projekttitel Englisch: MEMPROT-NET: The targeting and biosynthesis of membrane and secretory proteins

Schlüsselwörter (Englisch)

Protein synthesis; membrane proteins; secretory proteins; signal recognition particle;
Biotechnology; Environmental Protection; Innovation; Technology Transfer; Life Sciences; Medicine; Health; Waste Management

Alternative Projektnummern (Englisch)

EU project number: QLK3-2000-00082

Forschungsprogramme (Englisch)

EU-programme: 5. Frame Research Programme - 1.1.3 The 'cell factory'

Kurzbeschreibung (Englisch)

See abstract

Weitere Hinweise und Angaben (Englisch)

Full name of research-institution/enterprise:
Université de Genève
Faculté des Sciences
Département de Biologie cellulaire / Sciences III

Partner und Internationale Organisationen (Englisch)

Coordinator: Victoria University of Manchester (UK)

Abstract (Englisch)

Our objective is to - provide a detailed understanding of the biosynthesis of membrane and secretory proteins.

The focus will be:
1) components
2) molecular mechanisms and
3) regulation.

A detailed molecular understanding of these key issues is currently lacking. Furthermore, although membrane protein biosynthesis is directly relevant to exploiting the cell factory, little effort has been made to establish whether this process can be engineered. We will achieve our objective by focusing the research efforts of individual teams into a co-ordinated research programme.

The teams provide several different biological systems, enabling information and technology transfer, and represent all of the disciplines crucial to the project:
biochemistry;
cell biology;
microbiology;
structural biology;
bio-computing and commercial exploitation.

Datenbankreferenzen (Englisch)

Swiss Database: Euro-DB of the
State Secretariat for Education and Research
Hallwylstrasse 4
CH-3003 Berne, Switzerland
Tel. [phone]
Swiss Project-Number: 00.0258